| 2024-06-10 |
Evaluating the oral delivery of GalNAc-conjugated siRNAs in rodents and non-human primates |
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| 2024-06-10 |
Riboswitch and small RNAs modulate btuB translation initiation in Escherichia coli and trigger distinct mRNA regulatory mechanisms |
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| 2024-06-10 |
Kinetic pathway of HIV-1 TAR cotranscriptional folding |
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| 2024-06-10 |
Massively parallel dissection of RNA in RNA–protein interactions in vivo |
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| 2024-06-10 |
Constraints on the emergence of RNA through non-templated primer extension with mixtures of potentially prebiotic nucleotides |
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| 2024-06-10 |
Transcription factor shapes chromosomal conformation and regulates gene expression in bacterial adaptation |
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| 2024-06-10 |
Identification and in vitro characterization of UDP-GlcNAc-RNA cap-modifying and decapping enzymes |
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| 2024-06-10 |
Prokaryotic Argonaute nuclease cooperates with co-encoded RNase to acquire guide RNAs and target invader DNA |
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| 2024-06-10 |
Fluoropyrimidines trigger decay of hypomodified tRNA in yeast |
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| 2024-06-10 |
Structural snapshots of phenuivirus cap-snatching and transcription |
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| 2024-06-10 |
A bisulfite-assisted and ligation-based qPCR amplification technology for locus-specific pseudouridine detection at base resolution |
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| 2024-06-10 |
UPF1 helicase orchestrates mutually exclusive interactions with the SMG6 endonuclease and UPF2 |
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| 2024-06-10 |
Structural basis of archaeal RNA polymerase transcription elongation and Spt4/5 recruitment |
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| 2024-06-10 |
Arrayed in vivo barcoding for multiplexed sequence verification of plasmid DNA and demultiplexing of pooled libraries |
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| 2024-06-10 |
Correction |
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| 2024-06-10 |
BGCFlow: systematic pangenome workflow for the analysis of biosynthetic gene clusters across large genomic datasets |
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| 2024-06-10 |
Systematic identification of cargo-mobilizing genetic elements reveals new dimensions of eukaryotic diversity |
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| 2024-06-10 |
Functional redundancy in tRNA dihydrouridylation |
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| 2024-06-10 |
Correction to ‘The levels of p53 govern the hierarchy of DNA damage tolerance pathway usage’ |
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| 2024-06-10 |
Short 2′-O-methyl/LNA oligomers as highly-selective inhibitors of miRNA production in vitro and in vivo |
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| 2024-06-10 |
Correction to ‘Human CDK18 promotes replication stress signaling and genome stability’ |
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| 2024-06-10 |
Multivalent DNAzyme agents for cleaving folded RNA |
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| 2024-06-10 |
Correction to ‘PGS-Depot: a comprehensive resource for polygenic scores constructed by summary statistics based methods’ |
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| 2024-06-10 |
Expression of Concern on ‘MCPIP1 ribonuclease exhibits broad-spectrum antiviral effects through viral RNA binding and degradation’ |
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| 2024-06-10 |
The ABCF proteins in Escherichia coli individually cope with ‘hard-to-translate’ nascent peptide sequences |
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| 2024-06-10 |
Systematic interrogation of CRISPR antimicrobials in Klebsiella pneumoniae reveals nuclease-, guide- and strain-dependent features influencing antimicrobial activity |
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| 2024-06-10 |
Towards parsimonious generative modeling of RNA families |
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| 2024-06-10 |
Precise editing of pathogenic nucleotide repeat expansions in iPSCs using paired prime editor |
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| 2024-06-10 |
The mutation R107Q alters mtSSB ssDNA compaction ability and binding dynamics |
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| 2024-06-10 |
Human AAA+ ATPase FIGNL1 suppresses RAD51-mediated ultra-fine bridge formation |
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| 2024-06-10 |
Somatic and intergenerational G4C2 hexanucleotide repeat instability in a human C9orf72 knock-in mouse model |
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| 2024-06-10 |
Ordered and disordered regions of the Origin Recognition Complex direct differential in vivo binding at distinct motif sequences |
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| 2024-06-10 |
ARID1A regulates DNA repair through chromatin organization and its deficiency triggers DNA damage-mediated anti-tumor immune response |
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| 2024-06-10 |
Disruption of G-quadruplex dynamicity by BRCA2 abrogation instigates phase separation and break-induced replication at telomeres |
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| 2024-06-10 |
SIX2 promotes cell plasticity via Wnt/β-catenin signalling in androgen receptor independent prostate cancer |
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| 2024-06-10 |
PbARID-associated chromatin remodeling events are essential for gametocyte development in Plasmodium |
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| 2024-06-10 |
ARGLU1 enhances promoter-proximal pausing of RNA polymerase II and stimulates DNA damage repair |
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| 2024-06-10 |
APLF facilitates interstrand DNA crosslink repair and replication fork protection to confer cisplatin resistance |
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| 2024-06-10 |
The zinc-finger protein Z4 cooperates with condensin II to regulate somatic chromosome pairing and 3D chromatin organization |
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| 2024-06-10 |
Dux activates metabolism-lactylation-MET network during early iPSC reprogramming with Brg1 as the histone lactylation reader |
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| 2024-06-10 |
FUS reads histone H3K36me3 to regulate alternative polyadenylation |
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| 2024-06-10 |
Molecular insights into the fine-tuning of pH-dependent ArsR-mediated regulation of the SabA adhesin in Helicobacter pylori |
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| 2024-06-10 |
Two redundant transcription factor binding sites in a single enhancer are essential for mammalian sex determination |
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| 2024-06-10 |
Conserved intronic secondary structures with concealed branch sites regulate alternative splicing of poison exons |
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| 2024-06-10 |
Substrate specificity of Mycobacterium tuberculosis tRNA terminal nucleotidyltransferase toxin MenT3 |
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| 2024-06-10 |
Implication of nucleotides near the 3′ end of 16S rRNA in guarding the translational reading frame |
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| 2024-06-10 |
An alphacoronavirus polymerase structure reveals conserved replication factor functions |
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| 2024-06-10 |
Splicing analysis of STAT3 tandem donor suggests non-canonical binding registers for U1 and U6 snRNAs |
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| 2024-06-10 |
Ribosomal quality control factors inhibit repeat-associated non-AUG translation from GC-rich repeats |
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| 2024-05-22 |
High-density generation of spatial transcriptomics with STAGE |
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| 2024-05-22 |
Comprehensive genomic features indicative for Notch responsiveness |
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| 2024-05-22 |
SifiNet: a robust and accurate method to identify feature gene sets and annotate cells |
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| 2024-05-22 |
Genome-wide screening and functional validation of methylation barriers near promoters |
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| 2024-05-22 |
The discovery of novel noncoding RNAs in 50 bacterial genomes |
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| 2024-05-22 |
Comprehensive profiling of L1 retrotransposons in mouse |
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| 2024-05-22 |
Live-cell imaging reveals the trade-off between target search flexibility and efficiency for Cas9 and Cas12a |
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| 2024-05-22 |
Caspase-mediated processing of TRBP regulates apoptosis during viral infection |
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| 2024-05-22 |
SARS-CoV-2 nsp15 preferentially degrades AU-rich dsRNA via its dsRNA nickase activity |
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| 2024-05-22 |
m6ACali: machine learning-powered calibration for accurate m6A detection in MeRIP-Seq |
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| 2024-05-22 |
Biochemical and structural characterization of Fapy•dG replication by Human DNA polymerase β |
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| 2024-05-22 |
Examining chromatin heterogeneity through PacBio long-read sequencing of M.EcoGII methylated genomes: an m6A detection efficiency and calling bias correcting pipeline |
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| 2024-05-22 |
Correction to ‘STIM1 translocation to the nucleus protects cells from DNA damage’ |
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| 2024-05-22 |
A novel transient receptor potential C3/C6 selective activator induces the cellular uptake of antisense oligonucleotides |
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| 2024-05-22 |
Fourteen years of cellular deconvolution: methodology, applications, technical evaluation and outstanding challenges |
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| 2024-05-22 |
Activity reconstitution of Kre33 and Tan1 reveals a molecular ruler mechanism in eukaryotic tRNA acetylation |
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| 2024-05-22 |
Quantifying the activity profile of ASO and siRNA conjugates in glioblastoma xenograft tumors in vivo |
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| 2024-05-22 |
CRISPR-Cas tools for simultaneous transcription & translation control in bacteria |
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| 2024-05-22 |
Retraction of ‘Dissecting the splicing mechanism of the Drosophila editing enzyme; dADAR’ |
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| 2024-05-22 |
Definition of the binding specificity of the T7 bacteriophage primase by analysis of a protein binding microarray using a thermodynamic model |
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| 2024-05-22 |
NetActivity enhances transcriptional signals by combining gene expression into robust gene set activity scores through interpretable autoencoders |
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| 2024-05-22 |
RecA-dependent or independent recombination of plasmid DNA generates a conflict with the host EcoKI immunity by launching restriction alleviation |
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| 2024-05-22 |
SIRT2 promotes base excision repair by transcriptionally activating OGG1 in an ATM/ATR-dependent manner |
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| 2024-05-22 |
Defective transfer of parental histone decreases frequency of homologous recombination by increasing free histone pools in budding yeast |
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|
| 2024-05-22 |
S-phase checkpoint prevents leading strand degradation from strand-associated nicks at stalled replication forks |
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| 2024-05-22 |
Defining the contribution of microRNA-specific Argonautes with slicer capability in animals |
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| 2024-05-22 |
ATRX guards against aberrant differentiation in mesenchymal progenitor cells |
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| 2024-05-22 |
Catalytic residues of microRNA Argonautes play a modest role in microRNA star strand destabilization in C. elegans |
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|
| 2024-05-22 |
Viral reprogramming of host transcription initiation |
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| 2024-05-22 |
WSB1/2 target chromatin-bound lysine-methylated RelA for proteasomal degradation and NF-κB termination |
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| 2024-05-22 |
Correction of non-random mutational biases along a linear bacterial chromosome by the mismatch repair endonuclease NucS |
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| 2024-05-22 |
HBO1 determines SMAD action in pluripotency and mesendoderm specification |
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| 2024-05-22 |
CSB and SMARCAL1 compete for RPA32 at stalled forks and differentially control the fate of stalled forks in BRCA2-deficient cells |
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|
| 2024-05-22 |
RNA–RNA interactions between respiratory syncytial virus and miR-26 and miR-27 are associated with regulation of cell cycle and antiviral immunity |
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| 2024-05-22 |
DNA-PKcs suppresses illegitimate chromosome rearrangements |
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| 2024-05-22 |
UPF1 ATPase autoinhibition and activation modulate RNA binding kinetics and NMD efficiency |
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| 2024-05-22 |
Tracking pairwise genomic loci by the ParB–ParS and Noc-NBS systems in living cells |
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| 2024-05-22 |
LC3B drives transcription-associated homologous recombination via direct interaction with R-loops |
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| 2024-05-22 |
The jet-like chromatin structure defines active secondary metabolism in fungi |
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| 2024-05-22 |
Processivity and specificity of histone acetylation by the male-specific lethal complex |
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| 2024-05-22 |
RNA-binding properties orchestrate TDP-43 homeostasis through condensate formation in vivo |
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| 2024-05-22 |
Dynamics of miRNA accumulation during C. elegans larval development |
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| 2024-05-22 |
Nuclear RNA-related processes modulate the assembly of cytoplasmic RNA granules |
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| 2024-05-22 |
Cryo-EM structure of SRP68/72 reveals an extended dimerization domain with RNA-binding activity |
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| 2024-05-22 |
A Fur family protein BosR is a novel RNA-binding protein that controls rpoS RNA stability in the Lyme disease pathogen |
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| 2024-05-22 |
A combinatorial approach for achieving CNS-selective RNAi |
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|
| 2024-05-08 |
Structure-functional characterization of Lactococcus AbiA phage defense system |
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| 2024-05-08 |
Identifying human pre-mRNA cleavage and polyadenylation factors by genome-wide CRISPR screens using a dual fluorescence readthrough reporter |
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| 2024-05-08 |
Mutation rate heterogeneity at the sub-gene scale due to local DNA hypomethylation |
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| 2024-05-08 |
Correction to ‘Non-CpG methylation by DNMT3B facilitates REST binding and gene silencing in developing mouse hearts’ |
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| 2024-05-08 |
Discovery of a polymorphic gene fusion via bottom-up chimeric RNA prediction |
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